...The above doesn't mean it will not work with other configurations, OS's, DB's, etc, but we only provide INSTALL instructions for the above configuration. In fact PHP-Nuke works under Windows (all), FreeBSD, OS/2, MacOS, etc.
You see, it is always a good idea to read the INSTALL file that comes with a software package.
To see the PHP version you are running and do also a small test on your configuration, you can run the test.php file as described in Section 18.104.22.168.
PHP-Nuke and databases other than MySQL
From PHP-Nuke version 5.3, Francisco added a new SQL abstraction layer. It enables PHP-Nuke to support databases other than MySQL,
like mSQL, PostgreSQL, PostgreSQL_local, ODBC, ODBC_Adabas, Sybase and Interbase.
For the Microsoft Internet Informaion Server (IIS), some tests we have done were positive, some others indicated that a special configuration was needed.